Stem Cell Treatments

SCLERODERMA

Scleroderma is caused by the production of high levels of collagen. If only the skin is involved the skin may be discolored, inelastic, dry, thick and tight. The condition is an auto-immune disease and various antibodies may occur that result in systemic disease.

Laboratory tests requested will include ANA, anti-endothelial cell, anti-topisomerase, anti-Pm-Sci, anti-centromere, anti-ThRNP, anti-matrix metalloproteinase, anti-U3 RNP, anti-fibrillin, anti-platelet derived growth factor.

Depending upon which antibodies are present the disease can be systemic and involve various organs including the heart, lungs, kidneys, joints and intestinal tract.

Standard treatment consists of anti-inflammatories and steroids to suppress the antibodies targeting major organs.

StemCellRegenMed offers a different approach to this condition aiming at restoring the immune system. Patients will receive the following:

Autologous stem cells from the patient’s own bone marrow or peripheral blood.
Mesenchymal stem cells extracted from umbilical cord blood are given intravenously.
Anti-TFG beta (anti-transforming growth factor beta) is given i.v. to reduce skin and lung fibrosis; anti-CD19 that lowers antibodies and B cell function; nti-IL-6 that acts against inflammation and fibrosis.

Other agents appear promising and used in severe cases such as activator protein-1 which regulates transforming growth factor-beta ; also anti-fibroblast antibodies and Imatinib that reduces fibroblasts. This can be a serious disease and the approach to use immunotherapy to target the damaging antibodies is in the direction of getting at the cause of the disease.

Medical Disclaimer: Treatments discussed on this website are experimental and have not been approved by the FDA. No guarantees are made regarding the results of these treatments. Prospective patients are advised to discuss the use of a Stem Cell treatment for their disease with their physician.


		SCLERODERMA Scleroderma is caused by the production of high levels of collagen. If only the skin is involved the skin may be discolored, inelastic, dry, thick and tight. The condition is an auto-immune disease and various antibodies may occur that result in systemic disease. Laboratory tests requested will include ANA, anti-endothelial cell, anti-topisomerase, anti-Pm-Sci, anti-centromere, anti-ThRNP, anti-matrix metalloproteinase, anti-U3 RNP, anti-fibrillin, anti-platelet derived growth factor. Depending upon which antibodies are present the disease can be systemic and involve various organs including the heart, lungs, kidneys, joints and intestinal tract. Standard treatment consists of anti-inflammatories and steroids to suppress the antibodies targeting major organs. StemCellRegenMed offers a different approach to this condition aiming at restoring the immune system. Patients will receive the following: Autologous stem cells from the patient’s own bone marrow or peripheral blood. Mesenchymal stem cells extracted from umbilical cord blood are given intravenously. Anti-TFG beta (anti-transforming growth factor beta) is given i.v. to reduce skin and lung fibrosis; anti-CD19 that lowers antibodies and B cell function; nti-IL-6 that acts against inflammation and fibrosis. Other agents appear promising and used in severe cases such as activator protein-1 which regulates transforming growth factor-beta ; also anti-fibroblast antibodies and Imatinib that reduces fibroblasts. This can be a serious disease and the approach to use immunotherapy to target the damaging antibodies is in the direction of getting at the cause of the disease. Medical Disclaimer: Treatments discussed on this website are experimental and have not been approved by the FDA. No guarantees are made regarding the results of these treatments. Prospective patients are advised to discuss the use of a Stem Cell treatment for their disease with their physician.